Backup Now! 5 offers the usual basics: full and incremental backup, scheduling, and a compare function. It also has a nice set of utilities that display information about your drives, network and system. Unfortunately in my testing it failed to back up some open files (files in use by the OS or other programs).
At $49.99, Backup Now! is pricey for a program with no disaster recovery. However, combined in the $59.99 Deluxe Suite with the Drive Backup imaging component that has that feature it's a much better deal. Unfortunately, Drive Backup 5 and Deluxe Suite 5 weren?'t available yet, though according to NTI they should ship in November.
-Jon L. Jacobi