The interface can be a bit overwhelming upon launch. Hiding components (such as logs, status, transfer queues, and additional hosts) you don't need makes it much simpler. But the interface is eminently customizable, so you can show all of these panes and more if you like.
If you want to do simple FTP transfers to update a web site or just transfer files, SmartFTP Client will likely be more than you need. But if you are in your FTP client for much of the day or you need advanced functions, SmartFTP Client is worth checking out.