Minimalist for Everything lets you easily toggle off annoying interface elements in Gmail and Google Reader.
SlideDeck 2 for WordPress lets you create beautiful slide shows that pull in content from all over the web.
Rank Tracker lets you plot your search engine rankings over time.
Advanced Web Ranking is a cross-platform application for monitoring and improving your website's search rankings.
Market Samurai is a suite of tools for finding search terms worth ranking for.
Wix is a powerful online service for creating and hosting websites.
MojoMotor is a simple and affordable content management system for small websites.
XSite Pro is a WYSIWYG website creation tool with features for affiliate marketers.
Lavasoft adds a new Ad-Aware version to the lineup, updates Pro, and renames Ad-Aware Internet Security Free Internet Security to Ad-Aware Antivirus+.
Based on the Vim interface, Pentadactyl for Firefox lets you browse the Web without a mouse.
Part Instagram, part Flickr, Hipster lets users quickly customize photos and upload them for the world to enjoy.
Tomboy is a freeform database for text notes, with support for rich formatting and links.
MoinMoin is a powerful open source wiki with an optional desktop mode.
Zbar is a free, tiny, portable tool that puts a taskbar on your secondary monitor, and lets you pick different wallpapers for every monitor.
Free utility MultiMon Taskbar Free adds a simple taskbar to your secondary monitor...but even at that price, it may not be the best solution.