Dia

Dia can be used to draw many different kinds of diagrams. It currently has special objects to help draw entity relationship diagrams, UML diagrams, flowcharts, network diagrams, and simple circuits.

PhotoFiltre

Picture editor makes up for the few Photoshop features it doesn't have by being easier to use.

The Fifth Element

The Fifth Element is one of several suites from Ssuite (The double S is correct.) It aggresively tried to outdo Office with more features, simpler interface, and, of course, by being free

J. River MEDIA CENTER

Organizes and plays audio, video, images, TV, webmedia. Rips, burns and encodes.

ClipMate Clipboard Extender

More than a tweak to Windows clipboard, but a programmable database for tracking all sorts of info.

PDF Suite

Create professional-quality PDF documents for free.

Blender 3D

Blender is the first and only fully integrated 3D graphics creation suite allowing modeling, animation, rendering, post‑production, realtime interactive 3D and game creation and playback with cross‑platform compatibility.

Money Manager Ex

Money Manager Ex is an easy to use, money management application. It is a personal finance manager. It can be used to track your net worth, income vs expenses etc.

Soulseek

Soulseek not only figures out what song you'd like from the ones you've already downloaded, but it has a few secrets for anyone who bothers to read the documentaton on how to get faster and more complete downloads.

Kexi

Kexi is a great replacement for Access, particularly if your database is heavily graphic

Gnumeric

An Excel competitor that won't put a dent in your wallet.

Maya Personal Learning Edition

Award winning Autodesk Maya software is a powerful, integrated 3D modeling, animation, effects, and rendering solution.

Atlantis Nova

Great little word processor that does it all -- except charge you a bundle.

Wavosaur

Wavosaur is a free digital audio editing software which allows you to perform various operations with audio data such as visual editing, creating, recording, and playing audio files, applying VST audio effects,adding loop points, mastering your tracks.

Sharp Keys

Registry Hack to remap keyboard