I suppose most of us, at some time or another, have had a reason to use a computer with only one hand. But for those occasions, there’s StrokeIt. (Perhaps not the name I would have chosen….) StrokeIt allows you to issue commands and execute recorded actions using only mouse gestures.
It comes with enough predefined gestures to cover generic commands, such as save, open, and maximize, as well as gestures for particular programs, such as selecting tools in PhotoShop and the playback of music in popular media players.
Most of the gestures are simple to learn: O for open, N for new, P for play or print, depending on what program you’re using. You can add new gestures and new programs to control by moving your mouse. If you’re using them when I walk by, don’t get up. Just gesture. –Ron White